Dr Leighton Pritchard

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Contact

Personal statement

Please visit our group website: https://sipbs-compbiol.github.io/

Our group specialises in computational biology and bioinformatics, particularly for microbial genomics, but also in humans and plants. We have interests in taxonomy and classification of microbes, and the relationships between genome evolution and the different capabilities of organisms. We aim to understand links between genome and phenotype, such as the ability to produce - or resist - antibiotics, to produce enzymes and other products of biotechological value, the responses of human and plant cells to disease and infection, and the ways in which microbial pathogens interact with and control their hosts.

We study these areas using a range of techniques including phylogenetics and phylogenomics, comparative genomics and pangenomics, and mathematical and structural modelling.

You can follow the group (@SCompBiol), or me personally (@widdowquinn) on Twitter.

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Publications

pyANI-plus
Pritchard Leighton, Cock Peter, Kiepas Angelika
(2025)
Oxidative stress tolerance in the plant pathogen Pseudomonas syringae
Harper Chloe, Piat Julianna, Sanguankiattichai Nattapong, Pritchard Leighton, Uphoff Stephan, Preston Gail
2025 IS-MPMI Congress (2025)
The prevalence of Phytophthora in British plant nurseries : high-risk hosts and substrates and opportunities to influence practice
Green Sarah, Cooke David EL, Barwell Louise, Purse Bethan V, Cock Peter, Frederickson-Matika Debra, Randall Eva, Keillor Beatrix, Pritchard Leighton, Thorpe Peter, Pettit Tim, Schlenzig Alexandra, Barbrook Jane
Plant Pathology (2025)
https://doi.org/10.1111/ppa.14044
LINgroups as a robust principled approach to compare and integrate multiple bacterial taxonomies
Mazloom Reza, Pierce-Ward N Tessa, Sharma Parul, Pritchard Leighton, Brown C Titus, Vinatzer Boris A, Heath Lenwood S
IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol 21, pp. 2304-2314 (2024)
https://doi.org/10.1109/TCBB.2024.3475917
16S rRNA phylogeny and clustering is not a reliable proxy for genome-based taxonomy in Streptomyces
Kiepas Angelika B, Hoskisson Paul A, Pritchard Leighton
Microbial Genomics Vol 10 (2024)
https://doi.org/10.1099/mgen.0.001287
Biological ammonium transporters : evolution and diversification
Williamson Gordon, Harris Thomas, Bizior Adriana, Hoskisson Paul Alan, Pritchard Leighton, Javelle Arnaud
FEBS Journal Vol 291, pp. 3786-3810 (2024)
https://doi.org/10.1111/febs.17059

More publications

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Contact

Dr Leighton Pritchard
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: leighton.pritchard@strath.ac.uk
Tel: 548 4962